Nutribén® A.E.2 DIGEST

Nutribén® A.E.2 DIGEST is a complementary milk, recommended for babies over 6 months, that helps reduce constipation symptoms as it causes softer stools.

The main differentiating element of this formula is its special fat composition: it contains oil that is rich in palmitic acid in beta-position of the triglyceride (45%) that reduces the formation of calcium soaps, which are the main cause of constipation in babies. It also provides the following benefits:

  • Improves absorption of fats, achieving a better use of energy.1-2
  • Improves absorption of divalent metals such as calcium and magnesium.2
  • Softer stools.3
  • Reduces the formation of calcium soaps, thus decreasing constipation.3-4
  • Improves intestinal microbiota, making it similar to the microbiota of breastfed babies.5-6
  • Helps reduce intestinal inflammatory processes.7

Provides dietary fibre (galacto-oligosaccharides) that:8

  • Helps stimulate growth of bifidobacteria that are found in the colon.
  • Reduces constipation due to its fibre effect.
  • Strengthens the immune system.

It also contains nucleotides that improve intestinal development and reduce diarrhoea.9-14

– Check ingredients and product analysis.

Dosage table

This table is based on average requirements, and may only be varied if indicated by your doctor.

Levelled scoops*
Boiled water (ml)
Feeds per day
Age: 6 to 12 months
Age: 12 months and onwards

*One levelled scoop is equal to approximately 4.8 g.


IMPORTANT: This product is not intended to replace breast milk and should not be used as a substitute for breast milk. Nutribén® A.E.2 Digest is only suitable for children older than 6 months as part of a diversified diet. The decision to initiate complementary feeding should be taken only on the advice of the competent healthcare professional.

  1. 1. Carnielli VP, Luijendijk IHT, Van Goudoever JB, Sulkers EJ, Boerlage AA, Degenhart HJ, et al. Feeding premature newborns infants palmitic acid in amounts and stereoisomeric position similar to that of human milk: effects on fat, and mineral balance. Am J Clin Nutr 1995; 61: 1037-42.
  2. 2. Carnielli VP, Luijendijk IHT, Van Goudoever JB, Sulkers EJ, Boerlage AA, Degenhart HJ, et al. Structural position and amount of palmitic acid in infant formulas: effects on fat, fatty acid, and mineral balance. J Pediatr Gastroenterol Nutr 1996; 23: 553-60
  3. 3. Kennedy K, Fewtrell MS, Morley R, Abbott R, Quilan PT, Wells JCK, et al. Doubleblind, randomized trial of a synthetic triacylglycerol in formula fed-term infants:effects on stool biochemistry, stool characteristics, and bone mineralization. Am JClin Nutr 1999; 70: 920-7.
  4. 4. Quilan P. Structuring fats for incorporation into infant formulas. Fat in the Diet. Proceedings of the 21 st World Congress of the International Society for Fat Research (ISF), 1995 Oct; The Hague, Netherlands. Bridwater, UK: PJ Barnes & Associates; 1996. p. 21-6.
  5. 5. Yaron S, Shachar D, Abramas L, Riskin A, Bader D, Litmanovitz I, Bar-Yoseph F, Cohen T, Levi L, Lifshitz Y, Shamir R. Shaoul. Effect of high β-palmitate content in infant formula on the intestinal microbiota of term infants. J Pediatr Gastroenterol Nutr. 2013;56:376–81.
  6. 6. Yao M, Lien EL, Capeding MR, Fitzgerald M, Ramanujam K, Yuhas R, Nortington R, Lebumfacil J, Wang L, DeRusso PA. Effects of term infant formulas containing high sn-2 palmitate with and without oligofructose on stool composition, stool characteristics, and bifidogenicity: a randomized, double-blind, controlled trial. J Pediatr Gastroenterol Nutr. 2014;59:440
  7. 7. Lu P, Bar-Yoseph F, Levi L, Lifshitz Y, Witte-Bouma J, de Bruijn ACJM, Korteland-van Male AM, van Goudoever JB, Renes IB. High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice. PLoS One. 2013;8:e65878.
  8. 8. Supplementations of milk formula with galacto-oligosaccharides improve intestinal micro-flora and fermentation in term infant. Ben Xiao-Ming, Zhou Xiao-yu, Zhao Wei-hua, Yu Wen-liang, Pan Wei, Xhang Wei-li, Wu Sheng-mei, Christien M. Van Beusekom and Anne Schaafsma. Chinese Medical Journal, Vol 117 (6); 927-931. 2004.
  9. 9. Dietary sources of nucleotides- from breast milk to weaning. Barness LA. J. Nutr.1994: 128s-130s.
  10. 10. Dietary nucleotides: cellular immune, intestinal and hepatic system effects. J. Nutr1994: 124: 144-8s.
  11. 11. Modulation of the immune system by human milk and infant formula containing nucleotides. Pikering LK, Granoff DM, Erickson JR, Masor ML and cols. American Academy of Pediatrics. 1998; 101: 242-249
  12. 12. Alimentos funcionales. La importancia de los alimentos funcionales en las leches y papillas infantiles. Rivero Urgell M, Santamaría Orleáns A, Rodríguez Palmero, Seuma Mª. Nutrición Hospitalaria 2005; XX (2): 135-146.
  13. 13. Nucleotide supplementation and the growth of term small for gestational age infants. Cosgrove M. (1996) Arch Dis Childh 74 (f122-f125)
  14. 14. Effects of the addition of nucleotides to an adapted milk formula on the microbial pattern of faeces in at term new born infants. Gil A. (1986) J Clin. Nutr. Gastroent.1: 127-132.